PeptidesJuly 2, 2026

Peptides and the FDA: Where Things Actually Stand in 2026

Most longevity peptides sit in a legal gray zone right now, and an FDA meeting later this month could change that. What's restricted, what's under review, and what we can actually prescribe.

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LongevityMay 19, 2026

PDE5 Inhibitors: From the Bedroom to the Longevity Conversation

What the data actually says about sildenafil, tadalafil, and the link to lower all-cause mortality, cardiovascular events, and dementia risk.

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GLP-1April 28, 2026

Tirzepatide: the trials, the class, and the microdose question.

A walk through SURMOUNT and SURPASS, how tirzepatide stacks up against semaglutide, what microdosing actually means, and who benefits — beyond just BMI.

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TRTApril 21, 2026

Enclomiphene vs. TRT: Which should you try first?

A provider's honest comparison of enclomiphene and testosterone replacement therapy — fertility, the HPG axis, cost, and who's a candidate for each.

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TRTApril 10, 2026

Does TRT cause blood clots? What the TRAVERSE trial actually found.

A plain-English walkthrough of the largest randomized trial on testosterone therapy and cardiovascular safety — and what the clotting signal really means for men starting treatment.

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